In 1980, he founded the music group Einstürzende Neubauten, which has released numerous albums and singles, performed all over the world, and still exists to this day. His stage name comes from Blixa, a German brand of blue felt pen, and Bargeld, German for cash. Bargeld also refers to German Dada artist Johannes Theodor Baargeld.
From 1983 to 2003, Blixa Bargeld was a long-time guitarist and backing vocalist in Nick Cave and the Bad Seeds. Bargeld also sang several "co-lead" vocals with Cave, such as on "The Carny" and "The Weeping Song." Nick Cave first saw Bargeld performing with Einstürzende Neubauten on TV while The Birthday Party (Cave's band at the time) were touring in Amsterdam. He described the music as "mournful", Bargeld as looking "destroyed", and his screams as "a sound you would expect to hear from strangled cats or dying children."
He is credited with playing guitar on the Gun Club song, "Yellow Eyes", on their 1987 album Mother Juno.
Since the middle of the 90s Bargeld has appeared live with his "Solo Vocal Performance": during these performances, usually supported by Neubauten's sound engineer Boris Wilsdorf, he works with microphones, sound effects, overdubbing with the help of sampler loops, and speaks English or German. The performed pieces include such curiosities as a vocal creation of the DNA of an angel and a parody of a techno song.
In 2007 he started a collaborative project with Alva Noto called ANBB, an abbreviation of Noto's and Bargeld's initials. An EP, Ret Marut Handshake was released on June 26, 2010, followed later that year by a full-length album, "Mimikry".
Einstürzende Neubauten were celebrating their 30th anniversary in 2010 with a tour through Europe and the United States. Their European performances sold out in Brussels and Paris. They were planning to make rare performances in four US cities, including Los Angeles, San Francisco, Chicago and New York in December 2010, but the concerts were cancelled due to visa issues.